A polydimethylsiloxane (PDMS) deformable diffraction grating for monitoring of local pressure in microfluidic devices

被引:113
作者
Hosokawa, K [1 ]
Hanada, K [1 ]
Maeda, R [1 ]
机构
[1] Inst Mech Syst Engn, Tsukuba, Ibaraki 3058564, Japan
关键词
D O I
10.1088/0960-1317/12/1/301
中图分类号
TM [电工技术]; TN [电子技术、通信技术];
学科分类号
0808 [电气工程]; 0809 [电子科学与技术];
摘要
In this paper, a novel optical method for monitoring of local pressure in microfluidic devices using a deformable diffraction grating is presented. A test device was fabricated with transparent silicone elastomer-polydimethylsiloxane (PDMS)-using the replica moulding technique. The moulded PDMS chip and a flat glass plate have a bonding interface, which defines a 2 mm x 2 mm diffraction grating and a 200 mum wide, 20 mum deep microchannel. The grating consists of 5 mum wide, 2 mum deep rectangular grooves arrayed with a period of 10 mum. All the grooves are connected to the microchannel, and deformed by internal pressure. The optical response of the device to pressure ranging from -80 to 100 kPa is presented and compared with the theoretical prediction. It is also demonstrated that the test device can be used for measurement of air flow rates ranging from 0 to 0.3 ml min(-1). The major advantages of this method are simple design and inexpensive fabrication. This method is not only desirable for flow characterization of microfluidic devices, but also opens up the possibility of producing new types of fibre-optic pressure sensor and pressure-driven optical modulator.
引用
收藏
页码:1 / 6
页数:6
相关论文
共 20 条
[1]
AN ULTRASENSITIVE SILICON PRESSURE-BASED MICROFLOW SENSOR [J].
CHO, ST ;
NAJAFI, K ;
LOWMAN, CE ;
WISE, KD .
IEEE TRANSACTIONS ON ELECTRON DEVICES, 1992, 39 (04) :825-835
[2]
Patterned delivery of immunoglobulins to surfaces using microfluidic networks [J].
Delamarche, E ;
Bernard, A ;
Schmid, H ;
Michel, B ;
Biebuyck, H .
SCIENCE, 1997, 276 (5313) :779-781
[3]
*DOW CORN, 1991, 184 DOW CORN
[4]
Rapid prototyping of microfluidic systems in poly(dimethylsiloxane) [J].
Duffy, DC ;
McDonald, JC ;
Schueller, OJA ;
Whitesides, GM .
ANALYTICAL CHEMISTRY, 1998, 70 (23) :4974-4984
[5]
Integrated capillary electrophoresis on flexible silicone microdevices: Analysis of DNA restriction fragments and detection of single DNA molecules on microchips [J].
Effenhauser, CS ;
Bruin, GJM ;
Paulus, A ;
Ehrat, M .
ANALYTICAL CHEMISTRY, 1997, 69 (17) :3451-3457
[6]
Elastomeric optical elements with deformable surface topographies: applications to force measurements, tunable light transmission and light focusing [J].
Grzybowski, B ;
Qin, D ;
Haag, R ;
Whitesides, GM .
SENSORS AND ACTUATORS A-PHYSICAL, 2000, 86 (1-2) :81-85
[7]
Beam redirection and frequency filtering with transparent elastomeric diffractive elements [J].
Grzybowski, BA ;
Qin, D ;
Whitesides, GM .
APPLIED OPTICS, 1999, 38 (14) :2997-3002
[8]
Harrison D.J., 1998, MICROTOTAL ANAL SYST
[9]
A pneumatically-actuated three-way microvalve fabricated with polydimethylsiloxane using the membrane transfer technique [J].
Hosokawa, K ;
Maeda, R .
JOURNAL OF MICROMECHANICS AND MICROENGINEERING, 2000, 10 (03) :415-420
[10]
Handling of picoliter liquid samples in a poly(dimethylsiloxane)-based microfluidic device [J].
Hosokawa, K ;
Fujii, T ;
Endo, I .
ANALYTICAL CHEMISTRY, 1999, 71 (20) :4781-4785