One-Pot Synthesis of Spheres-on-Sphere Silica Particles from a Single Precursor for Fast HPLC with Low Back Pressure

被引：61

作者：

Ahmed, Adham ^{[1
]}

Ritchie, Harald ^{[2
]}

Myers, Peter ^{[1
]}

Zhang, Haifei ^{[1
]}

机构：

[1] Univ Liverpool, Dept Chem, Liverpool L69 7ZD, Merseyside, England

[2] Thermo Fisher Sci, Runcorn WA7 1TA, Cheshire, England

来源：

ADVANCED MATERIALS | 2012年 / 24卷 / 45期

关键词：

PERFORMANCE LIQUID-CHROMATOGRAPHY; MONOLITHIC COLUMNS; MICROSPHERES; POLYMER; NANOPARTICLES; CARBON; GOLD; CORE;

D O I：

10.1002/adma.201202810

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Spheres-on-sphere (SOS) silica particles are prepared in a one-pot scalable synthesis from mercaptopropyltrimethoxysilane with hydrophilic polymer and cationic surfactant under alkaline conditions. The SOS particles exhibit solid-core porous-shell properties. The fast separation of small molecules and proteins with low back pressure are demonstrated by high-performance liquid chromatography (HPLC) for the columns packed with SOS-particles. [GRAPHICS] .

引用

页码：6042 / +

页数：8

共 53 条

[1] Synthesis of Uniform Porous Silica Microspheres with Hydrophilic Polymer as Stabilizing Agent [J].

Ahmed, Adham ;

Clowes, Rob ;

Willneff, Elizabeth ;

Ritchie, Harald ;

Myers, Peter ;

Zhang, Haifei .

INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH, 2010, 49 (02) :602-608

[2] Novel one step fabrication of raspberry-like TiO2@yeast hybrid microspheres via electrostatic-interaction-driven self-assembled heterocoagulation for environmental applications [J].

Bai, Bo ;

Quici, Natalia ;

Li, Ziyan ;

Puma, Gianluca Li .

CHEMICAL ENGINEERING JOURNAL, 2011, 170 (2-3) :451-456

[3] One-Pot Colloidal Synthesis of Plasmonic Patchy Particles [J].

Bao, Huixin ;

Peukert, Wolfgang ;

Taylor, Robin N. Klupp .

ADVANCED MATERIALS, 2011, 23 (22-23) :2644-+

[4] 1.1 μm superficially porous particles for liquid chromatography. Part I: Synthesis and particle structure characterization [J].

Blue, Laura E. ;

Jorgenson, James W. .

JOURNAL OF CHROMATOGRAPHY A, 2011, 1218 (44) :7989-7995

[5] Fused-core, sub-2 μm packings, and monolithic HPLC columns: a comparative evaluation [J].

Brice, Richard W. ;

Zhang, Xin ;

Colon, Luis A. .

JOURNAL OF SEPARATION SCIENCE, 2009, 32 (15-16) :2723-2731

[6]

Buchel G, 1998, ADV MATER, V10, P1036, DOI 10.1002/(SICI)1521-4095(199809)10:13<1036::AID-ADMA1036>3.0.CO

[7]

2-Z

[8]

Caruso F, 2001, ADV MATER, V13, P11, DOI 10.1002/1521-4095(200101)13:1<11::AID-ADMA11>3.0.CO

[9]

2-N

[10] Core/Shell Nanoparticles: Classes, Properties, Synthesis Mechanisms, Characterization, and Applications [J].

Chaudhuri, Rajib Ghosh ;

Paria, Santanu .

CHEMICAL REVIEWS, 2012, 112 (04) :2373-2433

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