In vitro activities of 10 combinations of antifungal agents against the multiresistant pathogen Scopulatiopsis brevicaulis

被引：56

作者：

Cuenca-Estrella, M ^{[1
]}

Gomez-Lopez, A ^{[1
]}

Buitrago, MJ ^{[1
]}

Mellado, E ^{[1
]}

Garcia-Effron, G ^{[1
]}

Rodriguez-Tudela, JL ^{[1
]}

机构：

[1] Inst Salud Carlos III, Ctr Nacl Microbiol, Serv Micol, Majadahonda 28220, Madrid, Spain

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 2006年 / 50卷 / 06期

关键词：

D O I：

10.1128/AAC.00162-06

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

The activities of 10 combinations of antifungal agents against 25 clinical isolates of Scopulariopsis brevicaulis were tested by the checkerboard technique. An average indifferent effect was detected for all combinations. Synergy was observed for some isolates and combinations, particularly with posaconazole-terbinafine (68% of strains), amphotericin B-caspofungin (60%), and posaconazole-caspofungin (48%).

引用

页码：2248 / 2250

页数：3

共 39 条

[1] In vitro antifungal susceptibilities of Scopulariopsis isolates [J].

Aguilar, C ;

Pujol, I ;

Guarro, J .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1999, 43 (06) :1520-1522

[2] In vitro synergy of caspofungin and amphotericin B against Aspergillus and Fusarium spp. [J].

Arikan, S ;

Lozano-Chiu, M ;

Paetznick, V ;

Rex, JH .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2002, 46 (01) :245-247

[3]

Baddley JW, 2000, J CLIN MICROBIOL, V38, P395

[4] Granulomatous skin infection caused by Scopulariopsis brevicaulis [J].

Bruynzeel, I ;

Starink, TM .

JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, 1998, 39 (02) :365-367

[5]

Carrillo-Munoz Alfonso Javier, 2005, Revista Iberoamericana de Micologia, V22, P110

[6] In vitro activity of ravuconazole against 923 clinical isolates of nondermatophyte filamentous fungi [J].

Cuenca-Estrella, M ;

Gomez-Lopez, A ;

Mellado, E ;

Garcia-Effron, G ;

Monzon, A ;

Rodriguez-Tudela, JL .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2005, 49 (12) :5136-5138

[7] Combinations of antifungal agents in therapy - what value are they? [J].

Cuenca-Estrella, M .

JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 2004, 54 (05) :854-869

[8] Scopulariopsis brevicaulis, a fungal pathogen resistant to broad-spectrum antifungal agents [J].

Cuenca-Estrella, M ;

Gomez-Lopez, A ;

Mellado, E ;

Buitrago, MJ ;

Monzón, A ;

Rodriguez-Tudela, JL .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2003, 47 (07) :2339-2341

[9] Combined activity in vitro of caspofungin, amphotericin B, and azole agents against itraconazole-resistant clinical isolates of Aspergillus fumigatus [J].

Cuenca-Estrella, M ;

Gomez-Lopez, A ;

Garcia-Effron, G ;

Alcazar-Fuoli, L ;

Mellado, E ;

Buitrago, MJ ;

Rodriguez-Tudela, JL .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2005, 49 (03) :1232-1235

[10]

de Hoog G.S., 2000, ATLAS CLIN FUNGI, VSecond

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