Design Strategy for DNA Rotaxanes with a Mechanically Reinforced PX100 Axle

被引:38
作者
Ackermann, Damian [1 ]
Jester, Stefan-S.
Famulok, Michael [1 ]
机构
[1] Univ Bonn, LIMES Inst, Chem Biol & Med Chem Unit, Kekule Inst Organ Chem & Biochem, Gerhard Domagk Str 1, D-53121 Bonn, Germany
基金
欧洲研究理事会;
关键词
DNA nanorings; DNA nanotechnology; DNA rotaxanes; paranemic crossover; pseudorotaxanes; DOUBLE-CROSSOVER MOLECULES; PARANEMIC CROSSOVER; FOLDING DNA; NANOTECHNOLOGY; ORIGAMI; MOTORS; MACHINES; NANOSTRUCTURES; NANOMECHANICS; ARCHITECTURES;
D O I
10.1002/anie.201202816
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Non-deformable axles based on paranemic crossover DNAs can serve as components for mechanically stable DNA rotaxanes. The required design strategies provide generally applicable guidelines for the incorporation of mechanically interlocked DNA architectures or even DNA origami structures. DNA rotaxanes with mechanically reinforced axles can serve as precursors for complex molecular machines capable of force transmission. Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
引用
收藏
页码:6771 / 6775
页数:5
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