Dapsone in prevention of recurrent neutrophilic eccrine hidradenitis

被引：38

作者：

Shear, NH

Knowles, SR

Shapiro, L

Poldre, P

机构：

[1] SUNNYBROOK HLTH SCI CTR,DEPT MED,DIV DERMATOL,TORONTO,ON M4N 3M5,CANADA

[2] SUNNYBROOK HLTH SCI CTR,DEPT MED,DIV CLIN PHARMACOL,TORONTO,ON M4N 3M5,CANADA

[3] SUNNYBROOK HLTH SCI CTR,DEPT MED,DIV HEMATOL,TORONTO,ON M4N 3M5,CANADA

[4] SUNNYBROOK HLTH SCI CTR,DEPT MED,ADVERSE DRUG REACT CLIN,TORONTO,ON M4N 3M5,CANADA

[5] UNIV TORONTO,TORONTO,ON,CANADA

来源：

JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY | 1996年 / 35卷 / 05期

关键词：

D O I：

10.1016/S0190-9622(96)90092-4

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

Neutrophilic eccrine hidradenitis has been described in patients with acute myelogenous leukemia and other malignant diseases, usually during chemotherapy. We describe a 46-year-old man with Hodgkin's disease in whom neutrophilic eccrine hidradenitis developed after each of the first two treatments with lomustine. Dapsone, 100 mg daily, was initiated 48 hours before the patient's third treatment with lomustine and was continued for 14 days. This regimen was successful in suppressing the reaction during the first course and three subsequent courses of lomustine.

引用

页码：819 / 822

页数：4

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