ACTOR - Aggregated Computational Toxicology Resource

被引：145

作者：

Judson, Richard ^{[1
]}

Richard, Ann ^{[1
]}

Dix, David ^{[1
]}

Houck, Keith ^{[1
]}

Elloumi, Fathi ^{[1
]}

Martin, Matthew ^{[1
]}

Cathey, Tommy

Transue, Thomas R.

Spencer, Richard

Wolf, Maritja

机构：

[1] US EPA, Natl Ctr Computat Toxicol, Res Triangle Pk, NC 27711 USA

来源：

TOXICOLOGY AND APPLIED PHARMACOLOGY | 2008年 / 233卷 / 01期

关键词：

ToxCast; ACToR; Database; HTS; Screening; Prioritization;

D O I：

10.1016/j.taap.2007.12.037

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

ACTOR (Aggregated Computational Toxicology Resource) is a database and set of software applications that bring into one central location many types and sources of data on environmental chemicals. Currently, the ACToR chemical database contains information on chemical structure, in vitro bioassays and in vivo toxicology assays derived from more than 150 sources including the U.S. Environmental Protection Agency (EPA), Centers for Disease Control (CDC), U.S. Food and Drug Administration (FDA), National Institutes of Health (NIH), state agencies, corresponding government agencies in Canada, Europe and Japan, universities, the World Health Organization (WHO) and non-governmental organizations (NGOs). At the EPA National Center for Computational Toxicology, ACToR helps manage large data sets being used in a high-throughput environmental chemical screening and prioritization program called Toxcast (TM). (C) Published by Elsevier Inc.

引用

页码：7 / 13

页数：7

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