Multiplexed bioactive paper based on GO@SiO2@CeO2 nanosheets for a low-cost diagnostics platform

被引：44

作者：

Deng, Liu ^{[1
]}

Chen, Chaogui ^{[2
]}

Zhu, Chengzhou ^{[2
]}

Dong, Shaojun ^{[2
]}

Lu, Hongmei ^{[1
]}

机构：

[1] Cent S Univ, Coll Chem & Chem Engn, Changsha 410083, Hunan, Peoples R China

[2] Chinese Acad Sci, Changchun Inst Appl Chem, State Key Lab Electroanalyt Chem, Changchun 130022, Peoples R China

来源：

BIOSENSORS & BIOELECTRONICS | 2014年 / 52卷

基金：

中国博士后科学基金; 中国国家自然科学基金;

关键词：

Graphene oxide; Cerium oxide; Bioactive paper; Enzyme mimic; Lateral flow; MICROFLUIDIC DEVICES; NANOPARTICLES;

D O I：

10.1016/j.bios.2013.09.005

中图分类号：

Q6 [生物物理学];

学科分类号：

071011 [生物物理学];

摘要：

In this paper, Graphene oxide@SiO2@CeO2 hybrid nanosheets (GSCs) have been successfully synthesized by the wet-chemical strategy. TEM, FITR and XPS were applied to characterize the morphology and composition of the nanosheets. The colorimetric assay of these nanosheets indicated that they possessed high intrinsic peroxidase activity, which should be ascribed to the combination of graphene oxide and CeO2. A fully integrated reagentless bioactive paper based on GSCs was fabricated, which were able to simultaneously detect glucose, lactate, uric acid and cholesterol. The results demonstrated that GSCs have great potential as an alternative to the commonly employed peroxidase in daily nursing and general physical examination. (C) 2013 Elsevier B.V. All rights reserved.

引用

收藏

页码：324 / 329

页数：6

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