Treatment of chronic hepatitis B: Recommendations from an Italian workshop

被引:43
作者
Carosi, G. [1 ]
Rizzetto, M. [2 ]
机构
[1] Univ Brescia, Dept Infect & Trop Dis, Brescia, Italy
[2] Univ Turin, Dept Gastroenterol, Turin, Italy
关键词
antiviral therapy; cirrhosis; HBV; HCV; HDV; HIV; immune suppressed;
D O I
10.1016/j.dld.2008.03.011
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
The changing scenario of hepatitis B virus therapy has encouraged the organisation of a workshop, endorsed by three Italian scientific societies, aimed at defining the current recommendations for hepatitis B virus treatment. Liver histology and stage of disease remain fundamental for treatment decisions; interferon and nucleoside/nucleotide analogues-based therapy represent different strategies for different phases of the hepatitis B virus disease. The recommendations defined: new and lower cut-off of hepatitis B virus-DNA for eligibility to therapy according to disease stage, how to optimise the use of nucleoside/nucleotide analogues and to individualise the monitoring of response and what to do with treatment failures. Specific recommendations have also been given for cirrhosis patients, those immune suppressed and co-infected with HIV and other hepatitis viruses. (C) 2008 Editrice Gastroenterologica Italiana S.r.l. Published by Elsevier Ltd. All rights reserved.
引用
收藏
页码:603 / 617
页数:15
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