Receptor-like kinase ACR4 restricts formative cell divisions in the Arabidopsis root

被引：296

作者：

De Smet, Ive ^{[1
,2
,5
]}

Vassileva, Valya ^{[1
,2
]}

De Rybel, Bert ^{[1
,2
]}

Levesque, Mitchell P. ^{[3
,4
]}

Grunewald, Wim ^{[1
,2
]}

Van Damme, Daniel ^{[1
,2
]}

Van Noorden, Giel ^{[1
,2
]}

Naudts, Mirande ^{[1
,2
]}

Van Isterdael, Gert ^{[1
,2
]}

De Clercq, Rebecca ^{[1
,2
]}

Wang, Jean Y. ^{[3
,4
]}

Meuli, Nicholas ^{[6
]}

Vanneste, Steffen ^{[1
,2
]}

Friml, Jiri ^{[1
,2
]}

Hilson, Pierre ^{[1
,2
]}

Juergens, Gerd ^{[5
]}

Ingram, Gwyneth C. ^{[6
]}

Inze, Dirk ^{[1
,2
]}

Benfey, Philip N. ^{[3
,4
]}

Beeckman, Tom ^{[1
,2
]}

机构：

[1] Univ Ghent VIB, Flanders Inst Biotechnol, Dept Plant Syst Biol, B-9052 Ghent, Belgium

[2] Univ Ghent, Dept Mol Genet, B-9052 Ghent, Belgium

[3] Duke Univ, Dept Biol, Ctr Syst Biol, Durham, NC 27708 USA

[4] Duke Univ, Inst Genome Sci & Policy, Ctr Syst Biol, Durham, NC 27708 USA

[5] Univ Tubingen, Ctr Plant Mol Biol ZMBP, D-72076 Tubingen, Germany

[6] Univ Edinburgh, Inst Mol Plant Sci, Edinburgh EH9 3JR, Midlothian, Scotland

来源：

SCIENCE | 2008年 / 322卷 / 5901期

基金：

美国国家科学基金会;

关键词：

D O I：

10.1126/science.1160158

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

During the development of multicellular organisms, organogenesis and pattern formation depend on formative divisions to specify and maintain pools of stem cells. In higher plants, these activities are essential to shape the final root architecture because the functioning of root apical meristems and the de novo formation of lateral roots entirely rely on it. We used transcript profiling on sorted pericycle cells undergoing lateral root initiation to identify the receptor-like kinase ACR4 of Arabidopsis as a key factor both in promoting formative cell divisions in the pericycle and in constraining the number of these divisions once organogenesis has been started. In the root tip meristem, ACR4 shows a similar action by controlling cell proliferation activity in the columella cell lineage. Thus, ACR4 function reveals a common mechanism of formative cell division control in the main root tip meristem and during lateral root initiation.

引用

页码：594 / 597

页数：4

共 21 条

[1] The maize CRINKLY4 receptor kinase controls a cell-autonomous differentiation response [J].