A gene expression map of the Arabidopsis root

被引:941
作者
Birnbaum, K
Shasha, DE
Wang, JY
Jung, JW
Lambert, GM
Galbraith, DW
Benfey, PN
机构
[1] Duke Univ, Dept Biol, Durham, NC 27708 USA
[2] NYU, Dept Biol, New York, NY 10003 USA
[3] NYU, Courant Inst Math Sci, New York, NY 10003 USA
[4] Univ Arizona, Dept Plant Sci, Tucson, AZ 85721 USA
关键词
D O I
10.1126/science.1090022
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
A global map of gene expression within an organ can identify genes with coordinated expression in localized domains, thereby relating gene activity to cell fate and tissue specialization. Here, we present localization of expression of more than 22,000 genes in the Arabidopsis root. Gene expression was mapped to 15 different zones of the root that correspond to cell types and tissues at progressive developmental stages. Patterns of gene expression traverse traditional anatomical boundaries and show cassettes of hormonal response. Chromosomal clustering defined some coregulated genes. This expression map correlates groups of genes to specific cell fates and should serve to guide reverse genetics.
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收藏
页码:1956 / 1960
页数:5
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