Self-assembled nanoreactors as highly active catalysts in the hydrolytic kinetic resolution (HKR) of epoxides in water

被引：106

作者：

Rossbach, BM

Leopold, K

Weberskirch, R

机构：

[1] Tech Univ Munich, Lehrstuhl Makromol Stoffe, Dept Chem, D-85747 Garching, Germany

[2] Tech Univ Munich, Dept Chem, Lehrbereich Anorgan Chem, Arbeitskreis Analyt Chem, D-85747 Garching, Germany

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2006年 / 45卷 / 08期

关键词：

epoxides; immobilization; kinetic resolution; polymers; self-assembly;

D O I：

10.1002/anie.200503291

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

CoIII(salen) complexes have been immobilized on amphiphilic block copolymers, which self-assemble in water to give micellar aggregates with a hydrophobic Co(salen) core and a water-soluble shell (see picture). These aggregates were used to catalyze the hydrolytic kinetic resolution (HKR) of racemic aromatic epoxides over four consecutive cycles and gave the epoxides in up to 99 % ee. H2salen = N,N′-bis(salicylidene)ethylenediamine. (Chemical Equation Presented). © 2006 Wiley-VCH Verlag GmbH & Co. KGaA.

引用

页码：1309 / 1312

页数：4

共 67 条

[1] POLY(ETHYLENE OXIDE)-POLY(PROPYLENE OXIDE)-POLY(ETHYLENE OXIDE) BLOCK-COPOLYMER SURFACTANTS IN AQUEOUS-SOLUTIONS AND AT INTERFACES - THERMODYNAMICS, STRUCTURE, DYNAMICS, AND MODELING [J].