Macrophage activation syndrome as the presenting manifestation of rheumatic diseases in childhood

被引：81

作者：

Avcin, Tadej

Tse, Shirley M. L.

Schneider, Rayfel

Ngan, Bo

Silverman, Earl D.

机构：

[1] Univ Toronto, Hosp Sick Children, Div Rheumatol, Toronto, ON M5G 1X8, Canada

[2] Univ Toronto, Hosp Sick Children, Dept Pathol, Toronto, ON M5G 1X8, Canada

来源：

JOURNAL OF PEDIATRICS | 2006年 / 148卷 / 05期

关键词：

D O I：

10.1016/j.jpeds.2005.12.070

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

We describe 3 patients who presented with features of macrophage activation syndrome (MAS) at the time of presentation of systemic lupus eryhematosus (SLE), systemic juvenile idiopathic arthritis, and Kawasaki disease. Immunohistochemical,l studies in the patient with SLE demonstrated extensive expression of CD163 on hemophagocyte macrophages, suggesting a possible role as a marker of MAS.

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页码：683 / 686

页数：4

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