Asymmetric activation of conformationally flexible monodentate phosphites for enantioselective hydrogenation

被引：51

作者：

Chen, WP ^{[1
]}

Xiao, JL ^{[1
]}

机构：

[1] Univ Liverpool, Dept Chem, Leverhulme Ctr Innovat Catalysis, Liverpool L69 7ZD, Merseyside, England

来源：

TETRAHEDRON LETTERS | 2001年 / 42卷 / 49期

基金：

英国工程与自然科学研究理事会;

关键词：

asymmetric activation; asymmetric hydrogenation; monodentate phosphites; biphenyl ligands; rhodium catalysts;

D O I：

10.1016/S0040-4039(01)01895-0

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A new method is presented with which achiral, conformationally flexible biphenylphosphites can be activated by easily available chiral alcohols to give monodentate phosphite ligands that are effective in rhodium-catalysed enantio selective hydrogenation. (C) 2001 Elsevier Science Ltd. All rights reserved.

引用

页码：8737 / 8740

页数：4

共 29 条

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Blackmond DG, 1999, ANGEW CHEM INT EDIT, V38, P2196, DOI 10.1002/(SICI)1521-3773(19990802)38:15<2196::AID-ANIE2196>3.0.CO

[2]

2-9

[3] Chiral cooperativity in diastereomeric diphosphite ligands: Effects on the rhodium-catalyzed enantioselective hydroformylation of styrene [J].