Atmospheric pressure matrix-assisted laser desorption/ionisation mass spectrometry: A review

被引：22

作者：

Creaser, CS ^{[1
]}

Ratcliffe, L ^{[1
]}

机构：

[1] Nottingham Trent Univ, Sch Biomed & Nat Sci, Interdisciplinary Biomed Res Ctr, Nottingham NG11 8NS, England

来源：

CURRENT ANALYTICAL CHEMISTRY | 2006年 / 2卷 / 01期

关键词：

atmospheric pressure; MALDI; mass spectrometry;

D O I：

10.2174/157341106775197420

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

Atmospheric pressure matrix-assisted laser desorption/ionization (AP-MALDI) was first introduced in 1999. In the last few years, there has been a rapid growth in publications describing the development and application of AP MALDI to the mass spectrometric analysis of peptides, polymers and oligosaccharides. This short review discusses recent advances in AP-MALDI, focusing on the analysis of biomolecules and the relative performance of MALDI at atmospheric pressure and in vacuo.

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页码：9 / 15

页数：7

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