Islington study of dementia subtypes in the community

被引:132
作者
Stevens, T
Livingston, G
Kitchen, G
Manela, M
Walker, Z
Katona, C
机构
[1] UCL Royal Free & Univ Coll Med Sch, Dept Psychiat & Behav Sci, London W1N 8AA, England
[2] Camden & Islington Community Serv NHS Trust, London, England
关键词
D O I
10.1192/bjp.180.3.270
中图分类号
R749 [精神病学];
学科分类号
100205 ;
摘要
Background Epidemiological studies of dementia subtypes have revealed widely varying distribution rates. There are almost no published community prevalence data for dementia with Lewy bodies (DLB) or the frontal lobe dementias (FLD). Aims To identify the distribution of dementia subtypes in a representative community population of older people. Method People aged greater than or equal to 65 years in randomised enumeration districts in Islington, north London, were screened using a reliable and valid questionnaire. People screened as having dementia were assessed in detail and diagnoses were made according to standard diagnostic criteria. Results Of 1085 people interviewed, 107 (9.86%) met screening criteria for dementia. Diagnoses were made for 72 people (67.3%). Distribution of subtypes varied according to the criteria used; the best-validated criteria yielding: Alzheimer's disease 31.3%; vascular dementia 21.9%; DLB 10.9%; and FLD 7.8% . Conclusions Alzheimer's disease is confirmed as the most common cause of dementia in older people, followed by vascular dementia. However, DLB and FLD occur sufficiently often to be seen frequently in clinical practice and should be incorporated into future editions of standard diagnostic criteria. Declaration of interest None.
引用
收藏
页码:270 / 276
页数:7
相关论文
共 33 条
[1]   WORD FLUENCY AND BRAIN DAMAGE [J].
BORKOWSKI, JG ;
BENTON, AL ;
SPREEN, O .
NEUROPSYCHOLOGIA, 1967, 5 (02) :135-+
[2]  
BRUN A, 1994, J NEUROL NEUROSUR PS, V57, P416
[3]  
Brunschwig B. S., 1987, COMMENTS INORG CHEM, V6
[4]   A COMPUTERIZED PSYCHIATRIC DIAGNOSTIC SYSTEM AND CASE NOMENCLATURE FOR ELDERLY SUBJECTS - GMS AND AGECAT [J].
COPELAND, JRM ;
DEWEY, ME ;
GRIFFITHSJONES, HM .
PSYCHOLOGICAL MEDICINE, 1986, 16 (01) :89-99
[5]   The effect of different diagnostic criteria on the prevalence of dementia [J].
Erkinjuntti, T ;
Ostbye, T ;
Steenhuis, R ;
Hachinski, V .
NEW ENGLAND JOURNAL OF MEDICINE, 1997, 337 (23) :1667-1674
[6]   MINI-MENTAL STATE - PRACTICAL METHOD FOR GRADING COGNITIVE STATE OF PATIENTS FOR CLINICIAN [J].
FOLSTEIN, MF ;
FOLSTEIN, SE ;
MCHUGH, PR .
JOURNAL OF PSYCHIATRIC RESEARCH, 1975, 12 (03) :189-198
[7]  
FORNO LS, 1988, J NEUROPATHOL EXP NE, V47, P354
[8]   CLINICAL-NEUROPATHOLOGICAL CORRELATIONS IN ALZHEIMERS-DISEASE AND RELATED DEMENTIAS [J].
GALASKO, D ;
HANSEN, LA ;
KATZMAN, R ;
WIEDERHOLT, W ;
MASLIAH, E ;
TERRY, R ;
HILL, R ;
LESSIN, P ;
THAL, LJ .
ARCHIVES OF NEUROLOGY, 1994, 51 (09) :888-895
[9]   Sensitivity and specificity of newly proposed clinical criteria for possible vascular dementia [J].
Gold, G ;
Giannakopoulos, P ;
MontesPaixao, C ;
Herrmann, FR ;
Mulligan, R ;
Michel, JP ;
Bouras, C .
NEUROLOGY, 1997, 49 (03) :690-694
[10]  
Gregory CA, 1997, INT J GERIATR PSYCH, V12, P375, DOI 10.1002/(SICI)1099-1166(199703)12:3<375::AID-GPS518>3.0.CO