Elemental fluorine .1. Synthesis of fluoroaromatic compounds

被引：29

作者：

Chambers, RD ^{[1
]}

Skinner, CJ ^{[1
]}

Hutchinson, J ^{[1
]}

Thomson, J ^{[1
]}

机构：

[1] UNIV DURHAM,SCI LABS,BNFL FLUOROCHEM LTD,DURHAM DH1 3LE,ENGLAND

来源：

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1 | 1996年 / 07期

关键词：

D O I：

10.1039/p19960000605

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Direct fluorination of 4-fluorobenzoic acid, as a model substrate in a variety of reaction media, shows that 98% formic acid and concentrated sulfuric acid are excellent for promoting electrophilic fluorination. A high degree of fluorination may be achieved using concentrated sulfuric acid, showing that in this medium fluorine will act as a powerful electrophile.

引用

页码：605 / 609

页数：5

共 28 条

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