Functional MRI of human primary somatosensory and motor cortex during median nerve stimulation

被引：95

作者：

Spiegel, J

Tintera, J

Gawehn, J

Stoeter, P

Treede, RD ^{[1
]}

机构：

[1] Univ Mainz, Inst Physiol & Pathophysiol, D-55099 Mainz, Germany

[2] Univ Hosp, Inst Neuroradiol, D-55131 Mainz, Germany

来源：

CLINICAL NEUROPHYSIOLOGY | 1999年 / 110卷 / 01期

关键词：

functional magnetic resonance imaging; median nerve stimulation; somatosensory cortex; motor cortex; human brain mapping; somatosensory evoked potential;

D O I：

10.1016/S0168-5597(98)00043-4

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Objectives: Somatosensory evoked potential (SEP) studies suggested that some early cortical SEP components may be generated in the primary motor cortex (M1) rather than the primary somatosensory cortex (S1). Methods: We now used functional magnetic resonance imaging (fMRI) to study activation of S1 and M1 by electrical median nerve stimulation in healthy volunteers. Results: The hand areas of both S1 and M1 showed significant activation (correlation coefficients >0.45) in 7 of 9 subjects (activated volume S1 > M1). For comparison, a sequential finger opposition task significantly activated S1 in 7 and M1 in all 9 subjects (activated volume M1 > S1). Conclusions: These data show that the electrical stimuli used for SEP recording lead to a functional activation of S1 as well as M1. (C) 1999 Elsevier Science Ireland Ltd. All rights reserved.

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页码：47 / 52

页数：6

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