Dissociation behavior of doubly-charged tryptic peptides: Correlation of gas-phase cleavage abundance with Ramachandran plots

被引：62

作者：

Huang, YY

Triscari, JM

Pasa-Tolic, L

Anderson, GA

Lipton, MS

Smith, RD

Wysocki, VH ^{[1
]}

机构：

[1] Univ Arizona, Dept Chem, Tucson, AZ 85721 USA

[2] Pacific NW Natl Lab, Richland, WA 99352 USA

[3] Sci Applicat Int Corp, Tucson, AZ 85711 USA

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2004年 / 126卷 / 10期

关键词：

D O I：

10.1021/ja038041t

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Analysis of fragmentation patterns from 5654 unique doubly charged tryptic peptides is obtained. Great variability of average relative abundance of bond cleavage is found between different amino acid combinations. There exist similarities as well as differences between b and y ions. Strong enhancement or suppression of cleavage gives insight into possible chemical interactions at reactive conformations formed by preferred phi?psi angles. Copyright © 2004 American Chemical Society.

引用

页码：3034 / 3035

页数：2

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