An Integrated Index for the Identification of Diabetic Retinopathy Stages Using Texture Parameters

被引:116
作者
Acharya, U. Rajendra [1 ]
Ng, E. Y. K. [2 ]
Tan, Jen-Hong [2 ]
Sree, S. Vinitha [2 ]
Ng, Kwan-Hoong [3 ]
机构
[1] Ngee Ann Polytech, Dept Elect & Comp Engn, Singapore, Singapore
[2] Nanyang Technol Univ, Coll Engn, Sch Mech & Aerosp Engn, Singapore 639798, Singapore
[3] Univ Malaya, Dept Biomed Imaging, Kuala Lumpur, Malaysia
关键词
Diabetes; Retinopathy; Classifier; Texture; Support vector machine; Fundus image; Index; AUTOMATIC DETECTION; LESIONS;
D O I
10.1007/s10916-011-9663-8
中图分类号
R19 [保健组织与事业(卫生事业管理)];
学科分类号
摘要
Diabetes is a condition of increase in the blood sugar level higher than the normal range. Prolonged diabetes damages the small blood vessels in the retina resulting in diabetic retinopathy (DR). DR progresses with time without any noticeable symptoms until the damage has occurred. Hence, it is very beneficial to have the regular cost effective eye screening for the diabetes subjects. This paper documents a system that can be used for automatic mass screenings of diabetic retinopathy. Four classes are identified: , and . We used 238 retinal fundus images in our analysis. Five different texture features such as homogeneity, correlation, short run emphasis, long run emphasis, and run percentage were extracted from the digital fundus images. These features were fed into a support vector machine classifier (SVM) for automatic classification. SVM classifier of different kernel functions (linear, radial basis function, polynomial of order 1, 2, and 3) was studied. Receiver operation characteristics (ROC) curves were plotted to select the best classifier. Our proposed system is able to identify the unknown class with an accuracy of 85.2%, and sensitivity, specificity, and area under curve (AUC) of 98.9%, 89.5%, and 0.972 respectively using SVM classifier with polynomial kernel of order 3. We have also proposed a new integrated DR index (IDRI) using different features, which is able to identify the different classes with 100% accuracy.
引用
收藏
页码:2011 / 2020
页数:10
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