The effects of physical activity and exercise on brain-derived neurotrophic factor in healthy humans: A review

被引：309

作者：

Huang, T. ^{[1
]}

Larsen, K. T. ^{[1
]}

Ried-Larsen, M. ^{[1
]}

Moller, N. C. ^{[1
]}

Andersen, L. B. ^{[1
,2
]}

机构：

[1] Univ Southern Denmark, Inst Sports Sci & Clin Biomech, Ctr Res Childhood Hlth, DK-5230 Odense M, Denmark

[2] Norwegian Sch Sport Sci, Dept Sports Med, Oslo, Norway

来源：

SCANDINAVIAN JOURNAL OF MEDICINE & SCIENCE IN SPORTS | 2014年 / 24卷 / 01期

关键词：

physical activity; exercise; brain-derived neurotrophic factor; cardiorespiratory fitness; cognitive function; FACTOR BDNF; CARDIORESPIRATORY FITNESS; METABOLIC SYNDROME; INDUCED INCREASE; GROWTH-FACTOR; RISK-FACTORS; SERUM BDNF; HIGH-FAT; PLASMA; PLASTICITY;

D O I：

10.1111/sms.12069

中图分类号：

G8 [体育];

学科分类号：

04 ; 0403 ;

摘要：

The purpose of this study was to summarize the effects of physical activity and exercise on peripheral brain-derived neurotrophic factor (BDNF) in healthy humans. Experimental and observational studies were identified from PubMed, Web of Knowledge, Scopus, and SPORT Discus. A total of 32 articles met the inclusion criteria. Evidence from experimental studies suggested that peripheral BDNF concentrations were elevated by acute and chronic aerobic exercise. The majority of the studies suggested that strength training had no influence on peripheral BDNF. The results from most observational studies suggested an inverse relationship between the peripheral BDNF level and habitual physical activity or cardiorespiratory fitness. More research is needed to confirm the findings from the observational studies.

引用

页码：1 / 10

页数：10

共 63 条

[1] Cardiovascular fitness is associated with cognition in young adulthood [J].

Aberg, Maria A. I. ;

Pedersen, Nancy L. ;

Toren, Kjell ;

Svartengren, Magnus ;

Backstrand, Bjorn ;

Johnsson, Tommy ;

Cooper-Kuhn, Christiana M. ;

Aberg, N. David ;

Nilsson, Michael ;

Kuhn, H. Georg .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2009, 106 (49) :20906-20911

[2] No exercise-induced increase in serum BDNF after cycling near a major traffic road [J].

Bos, I. ;

Jacobs, L. ;

Nawrot, T. S. ;

de Geus, B. ;

Torfs, R. ;

Panis, L. Int ;

Degraeuwe, B. ;

Meeusen, R. .

NEUROSCIENCE LETTERS, 2011, 500 (02) :129-132

[3]

BOUCHARD C, 1986, MED SCI SPORT EXER, V18, P639

[4] Determinants of serum brain-derived neurotrophic factor [J].

Bus, B. A. A. ;

Molendijk, M. L. ;

Penninx, B. J. W. H. ;

Buitelaar, J. K. ;

Kenis, G. ;

Prickaerts, J. ;

Elzinga, B. M. ;

Voshaar, R. C. Oude .

PSYCHONEUROENDOCRINOLOGY, 2011, 36 (02) :228-239

[5] Human and rat hepatic stellate cells express neurotrophins and neurotrophin receptors [J].

Cassiman, D ;

Denef, C ;

Desmet, VJ ;

Roskams, T .

HEPATOLOGY, 2001, 33 (01) :148-158

[6]

Centers for Disease Control and Prevention, 2010, ASS SCH BAS PHYS ACT, P1

[7] Relationship of serum brain-derived neurotrophic factor (BDNF) and health-related lifestyle in healthy human subjects [J].

Chan, Ka Lok ;

Tong, Kai Yu ;

Yip, Shea Ping .

NEUROSCIENCE LETTERS, 2008, 447 (2-3) :124-128

[8] The concentrations of serum, plasma and platelet BDNF are all increased by treadmill VO2max performance in healthy college men [J].

Cho, Hyun-chul ;

Kim, Jongkyu ;

Kim, Sungyeon ;

Son, Yeon Hee ;

Lee, Namju ;

Jung, Seung Ho .

NEUROSCIENCE LETTERS, 2012, 519 (01) :78-83

[9] Physical therapy intervention (PTI) increases plasma brain-derived neurotrophic factor (BDNF) levels in non-frail and pre-frail elderly women [J].

Coelho, F. M. ;

Pereira, D. S. ;

Lustosa, L. P. ;

Silva, J. P. ;

Dias, J. M. D. ;

Dias, R. C. D. ;

Queiroz, B. Z. ;

Teixeira, A. L. ;

Teixeira, M. M. ;

Pereira, L. S. M. .

ARCHIVES OF GERONTOLOGY AND GERIATRICS, 2012, 54 (03) :415-420

[10] Increased basal plasma brain-derived neurotrophic factor levels in sprint runners [J].

Correia, Paulo Roberto ;

Scorza, Fulvio Alexandre ;

da Silva, Sergio Gomes ;

Pansani, Aline ;

Toscano-Silva, Michelle ;

de Almeida, Antonio Carlos ;

Arida, Ricardo Mario .

NEUROSCIENCE BULLETIN, 2011, 27 (05) :325-329

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