Increased basal plasma brain-derived neurotrophic factor levels in sprint runners

被引：22

作者：

Correia, Paulo Roberto ^{[1
]}

Scorza, Fulvio Alexandre ^{[2
]}

da Silva, Sergio Gomes ^{[1
]}

Pansani, Aline ^{[2
]}

Toscano-Silva, Michelle ^{[1
]}

de Almeida, Antonio Carlos ^{[3
]}

Arida, Ricardo Mario ^{[1
]}

机构：

[1] Univ Fed Sao Paulo UNIFESP, Dept Physiol, Sao Paulo, Brazil

[2] Univ Fed Sao Paulo UNIFESP, Dept Neurol & Neurosurg, Sao Paulo, Brazil

[3] Univ Fed Sao Joao del Rei, Lab Neurociencia Expt & Computac, Sao Joao Del Rei, Brazil

来源：

NEUROSCIENCE BULLETIN | 2011年 / 27卷 / 05期

基金：

巴西圣保罗研究基金会;

关键词：

brain-derived neurotrophic factor; physical exercise; sprint; plasma; brain; human; HEALTHY-HUMAN SUBJECTS; ACUTE EXERCISE; GROWTH-FACTOR; FACTOR BDNF; STRENGTH; CELLS; RELEASE; HUMANS; MEN;

D O I：

10.1007/s12264-011-1531-5

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Objective Exercise is known to enhance circulating brain-derived neurotrophic factor (BDNF) levels in healthy humans. BDNF changes have been measured in endurance but not in strength exercise. The present study aimed to investigate whether anaerobic activity such as sprinting differentially alters basal plasma BDNF concentration. Methods Brazilian sprinters (100 m) at either the international (Olympics and Outdoor World Championships) (n = 14) or the domestic level (n = 8), and sedentary subjects (n = 15), were recruited. Plasma BDNF concentrations were analyzed by enzyme-linked immunosorbent assay. Results The basal plasma BDNF concentrations were significantly higher in the international and the domestic sprinters than in the sedentary subjects. In addition, sprinters at the international level had higher plasma BDNF concentrations than those at the domestic level. Conclusion Our findings suggest that increased basal plasma BDNF level is related to enhanced exercise performance.

引用

页码：325 / 329

页数：5

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