Effect of absorption enhancers on ciliated epithelium: A novel in vivo toxicity screening method using rotifers

被引：7

作者：

Adriaens, E

Voorspoels, J

Mertens, J

Remon, JP

机构：

[1] STATE UNIV GHENT,PHARMACEUT TECHNOL LAB,B-9000 GHENT,BELGIUM

[2] STATE UNIV GHENT,ECOL LAB,B-9000 GHENT,BELGIUM

来源：

PHARMACEUTICAL RESEARCH | 1997年 / 14卷 / 04期

关键词：

absorption enhancers; ciliotoxicity; rotifers; cyclodextrins; bile salts; phosphatidylcholine; BRACHIONUS-CALYCIFLORUS; INSULIN; EXCIPIENTS; TRANSPORT; INVITRO; TISSUE; RATS;

D O I：

10.1023/A:1012176322362

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

[No abstract available]

引用

页码：541 / 545

页数：5

共 17 条

[1] EPITHELIAL TRANSPORT OF DRUGS IN CELL-CULTURE .7. EFFECTS OF PHARMACEUTICAL SURFACTANT EXCIPIENTS AND BILE-ACIDS ON TRANSEPITHELIAL PERMEABILITY IN MONOLAYERS OF HUMAN INTESTINAL EPITHELIAL (CACO-2) CELLS
ANDERBERG, EK
NYSTROM, C
ARTURSSON, P
[J]. JOURNAL OF PHARMACEUTICAL SCIENCES, 1992, 81 (09) : 879 - 887
[2] INSULIN AND DIDECANOYL-L-ALPHA-PHOSPHATIDYLCHOLINE - INVITRO STUDY OF THE TRANSPORT THROUGH RABBIT NASAL MUCOSAL TISSUE
BECHGAARD, E
JORGENSEN, L
LARSEN, R
GIZURARSON, S
CARSTENSEN, J
HVASS, A
[J]. INTERNATIONAL JOURNAL OF PHARMACEUTICS, 1993, 89 (02) : 147 - 153
[3] RAPID TOXICITY ASSESSMENT USING ESTERASE BIOMARKERS IN BRACHIONUS-CALYCIFLORUS (ROTIFERA)
BURBANK, SE
SNELL, TW
[J]. ENVIRONMENTAL TOXICOLOGY AND WATER QUALITY, 1994, 9 (03): : 171 - 178
[4] NASAL ABSORPTION IN RATS .2. EFFECT OF ENHANCERS ON INSULIN ABSORPTION AND NASAL HISTOLOGY
CHANDLER, SG
ILLUM, L
THOMAS, NW
[J]. INTERNATIONAL JOURNAL OF PHARMACEUTICS, 1991, 76 (1-2) : 61 - 70
[5] THE EFFECTS OF PERMEATION ENHANCERS ON THE SURFACE-MORPHOLOGY OF THE RAT NASAL-MUCOSA - A SCANNING ELECTRON-MICROSCOPY STUDY
ENNIS, RD
BORDEN, L
LEE, WA
[J]. PHARMACEUTICAL RESEARCH, 1990, 7 (05) : 468 - 475
[6] THE INFLUENCE OF INSULIN AND SOME EXCIPIENTS USED IN NASAL INSULIN PREPARATIONS ON MUCOCILIARY CLEARANCE
GIZURARSON, S
MARRIOTT, C
MARTIN, GP
BECHGAARD, E
[J]. INTERNATIONAL JOURNAL OF PHARMACEUTICS, 1990, 65 (03) : 243 - 247
[7] POPULATION-DYNAMICS OF ROTIFERS AND ITS CONSEQUENCES FOR ECOTOXICOLOGY
HALBACH, U
[J]. HYDROBIOLOGIA, 1984, 109 (01) : 79 - 96
[8] EFFECTS OF ABSORPTION ENHANCERS ON HUMAN NASAL TISSUE CILIARY MOVEMENT INVITRO
HERMENS, WAJJ
HOOYMANS, PM
VERHOEF, JC
MERKUS, FWHM
[J]. PHARMACEUTICAL RESEARCH, 1990, 7 (02) : 144 - 146
[9] HORNING WB, 1985, US EPA
[10] CYST-BASED TOXICITY TESTS .8. SHORT-CHRONIC TOXICITY TESTS WITH THE FRESH-WATER ROTIFER BRACHIONUS-CALCIFLORUS
JANSSEN, CR
PERSOONE, G
SNELL, TW
[J]. AQUATIC TOXICOLOGY, 1994, 28 (3-4) : 243 - 258

← 1 2 →