Nutraceuticals - An emerging era in the treatment and prevention of cardiovascular diseases

被引:70
作者
Ramaa, CS [1 ]
Shirode, AR [1 ]
Mundada, AS [1 ]
Kadam, VJ [1 ]
机构
[1] Bharati Vidyapeeth Coll Pharm, Belapur 400614, Navi Mumbai, India
关键词
nutraceutical; cardiovascular diseases; coronary heart diseases; prebiotics; omega-3 fatty acids; functional foods;
D O I
10.2174/138920106775789647
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Foods and nutrients play a vital role in normal functioning of the body. They are helpful in maintaining the health of the individual and in reducing the risk of various diseases. Worldwide acceptance of this fact formed a recognition link between "nutrition" and "health" and the concept of "nutraceuticals" was evolved. Nutraceuticals are medicinal foods that play a role in maintaining well being, enhancing health, modulating immunity and thereby preventing as well as treating specific diseases. Thus the field of nutraceuticals call be envisioned as one of the missing blocks in the health benefit of an individual. More than any other disease, the etiology of cardiovascular disease reveals many risk factors that are amenable to nutraceutical intervention. The scientific literature shows that several ingredients marketed for use in dietary supplements address each of these. The ability of nutraceuticals to positively influence cardiovascular risk factors should be recognized as in enormous opportunity in the treatment of a highly prevalent disease. Nutraceuticals hold promise in clinical therapy as they have the potential to significantly reduce the risk. of side effects associated with chemotherapy along with reducing the global health care cost. In this review, an attempt has been made to summarize some of the recent research findings on garlic, omega-3-ratty acids, soy products, dietary fibres, vitamins, antioxidants, plant sterols, flavonoids, prebiotics and probiotics that have beneficial effects on the heart, in order to update the practising clinician on the benefit of using nutraceuticals for the management of cardiovascular diseases.
引用
收藏
页码:15 / 23
页数:9
相关论文
共 87 条
[71]  
SHINNICK FL, 1991, CEREAL FOOD WORLD, V36, P815
[72]  
SHRAPNEL B, 2001, CURR THER, V42, P45
[73]  
SILAGY C, 1999, J HYPERTENS, V12, P463
[75]  
Sinatra ST, 1997, MOL ASPECTS MED, V18, pS299
[76]  
Smirnov V. V., 1993, Mikrobiologicheskii Zhurnal (Kiev), V55, P92
[77]  
Soja AM, 1997, MOL ASPECTS MED, V18, pS159
[78]   Immediate effect of Lactobacillus acidophilus on the intestinal flora and fecal enzymes of rats and the in vitro inhibition of Escherichia coli in coculture [J].
Sreekumar, O ;
Hosono, A .
JOURNAL OF DAIRY SCIENCE, 2000, 83 (05) :931-939
[79]   VITAMIN-E CONSUMPTION AND THE RISK OF CORONARY-DISEASE IN WOMEN [J].
STAMPFER, MJ ;
HENNEKENS, CH ;
MANSON, JE ;
COLDITZ, GA ;
ROSNER, B ;
WILLETT, WC .
NEW ENGLAND JOURNAL OF MEDICINE, 1993, 328 (20) :1444-1449
[80]   Randomised controlled trial of vitamin E in patients with coronary disease: Cambridge Heart Antioxidant Study (CHAOS) [J].
Stephens, NG ;
Parsons, A ;
Schofield, PM ;
Kelly, F ;
Cheeseman, K ;
Mitchinson, MJ ;
Brown, MJ .
LANCET, 1996, 347 (9004) :781-786