Tackling both sides of the host-pathogen equation with Caenorhabditis elegans

被引：83

作者：

Ewbank, JJ ^{[1
]}

机构：

[1] Univ Mediterranee, CNRS, INSERM, Ctr Immunol Marseille Luminy, F-13288 Marseille 9, France

来源：

MICROBES AND INFECTION | 2002年 / 4卷 / 02期

关键词：

models; genetic; virulence; immunity; natural;

D O I：

10.1016/S1286-4579(01)01531-3

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

If one is interested in dissecting the complex interactions that exist between host and pathogen, the nematode worm Caenorhabditis elegans is perhaps not the first model host that comes to mind. In this review I will introduce 'the worm' and try to show how it is, in fact, well suited to the identification of universal virulence factors and holds great promise for the study of conserved mechanisms of innate immunity. (C) 2002 Editions scientifiques et medicales Elsevier SAS. All rights reserved.

引用

页码：247 / 256

页数：10

共 73 条

[1] Salmonella typhimurium proliferates and establishes a persistent infection in the intestine of Caenorhabditis elegans
Aballay, A
Yorgey, P
Ausubel, FM
[J]. CURRENT BIOLOGY, 2000, 10 (23) : 1539 - 1542
[2] Programmed cell death mediated by ced-3 and ced-4 protects Caenorhabditis elegans from Salmonella typhimurium-mediated killing
Aballay, A
Ausubel, FM
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2001, 98 (05) : 2735 - 2739
[3] EFFECT OF BACTERIA ON DISPERSAL OF CAENORHABDITIS-ELEGANS (RHABDITIDAE)
ANDREW, PA
NICHOLAS, WL
[J]. NEMATOLOGICA, 1976, 22 (04): : 451 - 461
[4] The natural history of Caenorhabditis elegans research
Ankeny, RA
[J]. NATURE REVIEWS GENETICS, 2001, 2 (06) : 474 - 479
[5] [Anonymous], 1997, C ELEGANS
[6] [Anonymous], 1988, NEMATODE CAENORHABDI
[7] Sugar binding properties of the two lectin domains of the tandem repeat-type galectin LEC-1 (N32) of Caenorhabditis elegans -: Detailed analysis by an improved frontal affinity chromatography method
Arata, Y
Hirabayashi, J
Kasai, K
[J]. JOURNAL OF BIOLOGICAL CHEMISTRY, 2001, 276 (05) : 3068 - 3077
[8] Amoebapore homologs of Caenorhabditis elegans
Bányai, L
Patthy, L
[J]. BIOCHIMICA ET BIOPHYSICA ACTA-PROTEIN STRUCTURE AND MOLECULAR ENZYMOLOGY, 1998, 1429 (01): : 259 - 264
[9] Bird A.F., 1980, P213
[10] Borgonie G, 1996, FUND APPL NEMATOL, V19, P523

← 1 2 3 4 5 6 7 8 →