Tackling both sides of the host-pathogen equation with Caenorhabditis elegans

被引：83

作者：

Ewbank, JJ ^{[1
]}

机构：

[1] Univ Mediterranee, CNRS, INSERM, Ctr Immunol Marseille Luminy, F-13288 Marseille 9, France

来源：

MICROBES AND INFECTION | 2002年 / 4卷 / 02期

关键词：

models; genetic; virulence; immunity; natural;

D O I：

10.1016/S1286-4579(01)01531-3

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

If one is interested in dissecting the complex interactions that exist between host and pathogen, the nematode worm Caenorhabditis elegans is perhaps not the first model host that comes to mind. In this review I will introduce 'the worm' and try to show how it is, in fact, well suited to the identification of universal virulence factors and holds great promise for the study of conserved mechanisms of innate immunity. (C) 2002 Editions scientifiques et medicales Elsevier SAS. All rights reserved.

引用

页码：247 / 256

页数：10

共 73 条

[11] Borgonie G, 1996, FUND APPL NEMATOL, V19, P391
[12] BORGONIE G, 1995, FUND APPL NEMATOL, V18, P227
[13] Borgonie G, 1996, FUND APPL NEMATOL, V19, P407
[14] BRENNER S, 1974, GENETICS, V77, P71
[15] Regulation of the Caenorhabditis elegans gut cysteine protease gene cpr-1:: Requirement for GATA motifs
Britton, C
McKerrow, JH
Johnstone, LL
[J]. JOURNAL OF MOLECULAR BIOLOGY, 1998, 283 (01) : 15 - 27
[16] THE AUTOFLUORESCENT LIPOFUSCIN GRANULES IN THE INTESTINAL-CELLS OF CAENORHABDITIS-ELEGANS ARE SECONDARY LYSOSOMES
CLOKEY, GV
JACOBSON, LA
[J]. MECHANISMS OF AGEING AND DEVELOPMENT, 1986, 35 (01) : 79 - 94
[17] Lethal paralysis of Caenorhabditis elegans by Pseudomonas aeruginosa
Darby, C
Cosma, CL
Thomas, JH
Manoil, C
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1999, 96 (26) : 15202 - 15207
[18] Predatory behaviour of trapping fungi against srf mutants of Caenorhabditis elegans and different plant and animal parasitic nematodes
de Gives, PM
Davies, KG
Clark, SJ
Behnke, JM
[J]. PARASITOLOGY, 1999, 119 : 95 - 104
[19] C-type lectin-like domains in Caenorhabditis elegans:: predictions from the complete genome sequence
Drickamer, K
Dodd, RB
[J]. GLYCOBIOLOGY, 1999, 9 (12) : 1357 - 1369
[20] LOCATION OF SPECIFIC MESSENGER-RNAS IN CAENORHABDITIS-ELEGANS BY CYTOLOGICAL HYBRIDIZATION
EDWARDS, MK
WOOD, WB
[J]. DEVELOPMENTAL BIOLOGY, 1983, 97 (02) : 375 - 390

← 1 2 3 4 5 6 7 8 →