Translating basic cancer research into new cancer therapeutics

被引:50
作者
Workman, P [1 ]
Kaye, SB
机构
[1] Inst Canc Res, Canc Res UK Ctr Canc Therapeut, Sutton SM2 5NG, Surrey, England
[2] Inst Canc Res, Med Sect, Sutton SM2 5NG, Surrey, England
[3] Royal Marsden Hosp, Sutton SM2 5NG, Surrey, England
关键词
D O I
10.1016/S1471-4914(02)02319-5
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
引用
收藏
页码:S1 / S9
页数:9
相关论文
共 15 条
[1]   Proliferation, cell cycle and apoptosis in cancer [J].
Evan, GI ;
Vousden, KH .
NATURE, 2001, 411 (6835) :342-348
[2]   Pharmacological rescue of mutant p53 conformation and function [J].
Foster, BA ;
Coffey, HA ;
Morin, MJ ;
Rastinejad, F .
SCIENCE, 1999, 286 (5449) :2507-2510
[3]   Discovering novel chemotherapeutic drugs for the third millennium [J].
Garrett, MD ;
Workman, P .
EUROPEAN JOURNAL OF CANCER, 1999, 35 (14) :2010-2030
[4]   Mechanism-based target identification and drug discovery in cancer research [J].
Gibbs, JB .
SCIENCE, 2000, 287 (5460) :1969-1973
[5]   The hallmarks of cancer [J].
Hanahan, D ;
Weinberg, RA .
CELL, 2000, 100 (01) :57-70
[6]   Choosing anticancer drug targets in the postgenomic era [J].
Kaelin, WG .
JOURNAL OF CLINICAL INVESTIGATION, 1999, 104 (11) :1503-1506
[7]   Histone acetylases and deacetylases in cell proliferation [J].
Kouzarides, T .
CURRENT OPINION IN GENETICS & DEVELOPMENT, 1999, 9 (01) :40-48
[8]   Initial sequencing and analysis of the human genome [J].
Lander, ES ;
Int Human Genome Sequencing Consortium ;
Linton, LM ;
Birren, B ;
Nusbaum, C ;
Zody, MC ;
Baldwin, J ;
Devon, K ;
Dewar, K ;
Doyle, M ;
FitzHugh, W ;
Funke, R ;
Gage, D ;
Harris, K ;
Heaford, A ;
Howland, J ;
Kann, L ;
Lehoczky, J ;
LeVine, R ;
McEwan, P ;
McKernan, K ;
Meldrim, J ;
Mesirov, JP ;
Miranda, C ;
Morris, W ;
Naylor, J ;
Raymond, C ;
Rosetti, M ;
Santos, R ;
Sheridan, A ;
Sougnez, C ;
Stange-Thomann, N ;
Stojanovic, N ;
Subramanian, A ;
Wyman, D ;
Rogers, J ;
Sulston, J ;
Ainscough, R ;
Beck, S ;
Bentley, D ;
Burton, J ;
Clee, C ;
Carter, N ;
Coulson, A ;
Deadman, R ;
Deloukas, P ;
Dunham, A ;
Dunham, I ;
Durbin, R ;
French, L .
NATURE, 2001, 409 (6822) :860-921
[9]  
Malozemoff A.P., 1990, HIGH TEMPERATURE SUP, P3
[10]   The language of covalent histone modifications [J].
Strahl, BD ;
Allis, CD .
NATURE, 2000, 403 (6765) :41-45