Antibiotic resistance - A vancomycin surprise

被引：24

作者：

Gilmore, MS ^{[1
]}

Hoch, JA

机构：

[1] Univ Oklahoma, Hlth Sci Ctr, Dept Ophthalmol, Oklahoma City, OK 73190 USA

[2] Univ Oklahoma, Hlth Sci Ctr, Dept Microbiol, Oklahoma City, OK 73190 USA

[3] Scripps Res Inst, Res Inst, Dept Mol & Expt Med, Div Cellular Biol, La Jolla, CA 92037 USA

来源：

NATURE | 1999年 / 399卷 / 6736期

关键词：

D O I：

10.1038/21070

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Bacteria are becoming increasingly clever, and can now outwit most of the antibiotics that we throw at them. The results of a new study show not only that some clinical isolates of penicillin-resistantS. pneumoniaeare also tolerant to vancomycin, but they also give us a clue to how the bacteria do this. The key is a two-component signal-transduction system.

引用

页码：524 / +

页数：3

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