Fluorescence bioimaging with conjugated polyelectrolytes

被引：80

作者：

Feng, Guangxue ^{[1
]}

Ding, Dan ^{[1
]}

Liu, Bin ^{[1
,2
]}

机构：

[1] Natl Univ Singapore, Dept Chem & Biomol Engn, Singapore 117576, Singapore

[2] Inst Mat Res & Engn, Singapore 117602, Singapore

来源：

NANOSCALE | 2012年 / 4卷 / 20期

基金：

新加坡国家研究基金会;

关键词：

POLYHEDRAL OLIGOMERIC SILSESQUIOXANE; RED/NEAR-INFRARED FLUORESCENCE; SENSITIVE OPTICAL PROBES; POLYMER NANOPARTICLES; QUANTUM DOTS; ANTITUMOR-ACTIVITY; DRUG-DELIVERY; CELLS; DNA; OLIGOELECTROLYTE;

D O I：

10.1039/c2nr31392h

中图分类号：

O6 [化学];

学科分类号：

070301 [无机化学];

摘要：

This review summarizes the recent developments in fluorescent conjugated polyelectrolytes (CPEs) in bioimaging. The CPEs discussed include linear-, hyperbranched-, and polyhedral oligomeric silsesquioxanes (POSS)-based derivatives. Originating from their special optical properties, good photostability, low cytotoxicity, ease of bioconjugation and tuneable size, CPEs have shown wide applications in in vitro and in vivo protein and cell imaging, drug tracking and gene delivery. Moreover, some CPEs also possess antibacterial and anticancer characteristics as well as apoptosis imaging functions. Finally, this review discusses the future outlook of CPEs in bioimaging applications.

引用

页码：6150 / 6165

页数：16

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