A practical guide to diagnostic transcranial magnetic stimulation: Report of an IFCN committee

被引:912
作者
Groppa, S. [2 ]
Oliviero, A. [3 ]
Eisen, A. [4 ]
Quartarone, A. [5 ]
Cohen, L. G. [6 ]
Mall, V. [7 ]
Kaelin-Lang, A. [8 ]
Mima, T. [9 ]
Rossi, S. [10 ]
Thickbroom, G. W. [11 ]
Rossini, P. M. [12 ,13 ]
Ziemann, U. [14 ]
Valls-Sole, J. [15 ]
Siebner, H. R. [1 ]
机构
[1] Copenhagen Univ Hosp Hvidovre, DRCMR, DK-2650 Hvidovre, Denmark
[2] Univ Kiel, Dept Neurol, D-2300 Kiel, Germany
[3] Hosp Nacl Paraplej, Toledo, Spain
[4] Univ British Columbia, Dept Neurol, Vancouver, BC V5Z 1M9, Canada
[5] Univ Messina, Dept Neurosci Psychiat & Anesthesiol, Messina, Italy
[6] Natl Inst Neurol Disorders & Stroke, Human Cort Physiol & Stroke Neurorehabil Sect, NIH, Bethesda, MD USA
[7] Univ Freiburg, Dept Neuropediat & Muscle Disorders, D-79106 Freiburg, Germany
[8] Univ Bern, Inselspital, Dept Neurol, CH-3010 Bern, Switzerland
[9] Univ Grad Sch Med, Human Brain Res Ctr, Kyoto, Japan
[10] Univ Siena, Dipartimento Neurosci, Sez Neurol & Neurofisiol Clin, Policlin Le Scotte, I-53100 Siena, Italy
[11] Univ Western Australia, Ctr Neuromuscular & Neurol Disorders, Nedlands, WA 6009, Australia
[12] Catholic Univ, Inst Neurol, Pol Gemelli, Italy
[13] IRCCS S Raffaele Pisana & Casa Cura S Raffaele Ca, Rome, Italy
[14] Goethe Univ Frankfurt, Dept Neurol, Frankfurt, Germany
[15] Univ Barcelona, Hosp Clin, Serv Neurol, Unitat EMG, E-08007 Barcelona, Spain
关键词
Transcranial magnetic stimulation; Clinical neurophysiology; Corticomotor conduction; Motor-evoked potentials; MOTOR EVOKED-POTENTIALS; INFLAMMATORY DEMYELINATING POLYNEUROPATHY; CENTRAL-NERVOUS-SYSTEM; SILENT PERIOD; BRAIN-STIMULATION; MULTIPLE-SCLEROSIS; CONSCIOUS HUMANS; CEREBRAL-CORTEX; NORMAL VALUES; INTERHEMISPHERIC DIFFERENCES;
D O I
10.1016/j.clinph.2012.01.010
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Transcranial magnetic stimulation (TMS) is an established neurophysiological tool to examine the integrity of the fast-conducting corticomotor pathways in a wide range of diseases associated with motor dysfunction. This includes but is not limited to patients with multiple sclerosis, amyotrophic lateral sclerosis, stroke, movement disorders, disorders affecting the spinal cord, facial and other cranial nerves. These guidelines cover practical aspects of TMS in a clinical setting. We first discuss the technical and physiological aspects of TMS that are relevant for the diagnostic use of TMS. We then lay out the general principles that apply to a standardized clinical examination of the fast-conducting corticomotor pathways with single-pulse TMS. This is followed by a detailed description of how to examine corticomotor conduction to the hand, leg, trunk and facial muscles in patients. Additional sections cover safety issues, the triple stimulation technique, and neuropediatric aspects of TMS. (C) 2012 International Federation of Clinical Neurophysiology. Published by Elsevier Ireland Ltd. All rights reserved.
引用
收藏
页码:858 / 882
页数:25
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