Preliminary report of biological basis of sensitivity to the effects of cannabis on psychosis: AKT1 and DAT1 genotype modulates the effects of δ-9-tetrahydrocannabinol on midbrain and striatal function

被引：91

作者：

Bhattacharyya, S. ^{[1
]}

Atakan, Z. ^{[1
]}

Martin-Santos, R. ^{[2
,3
]}

Crippa, J. A. ^{[4
]}

Kambeitz, J. ^{[1
]}

Prata, D. ^{[1
]}

Williams, S. ^{[5
]}

Brammer, M. ^{[5
]}

Collier, D. A. ^{[6
]}

McGuire, P. K. ^{[1
]}

机构：

[1] Kings Coll London, Dept Psychosis Studies, Inst Psychiat, London WC2R 2LS, England

[2] Univ Barcelona, Hosp del Mar, IMIM, Pharmacol Res Unit, Barcelona, Spain

[3] Univ Barcelona, Dept Psychiat & Clin Psychobiol, CIBERSAM, IDIBAPS,Hosp Clin Barcelona,ICN,Dept Psychiat, Barcelona, Spain

[4] Univ Sao Paulo, Fac Med Ribeirao Preto, Dept Neurol Psychiat & Med Psychol, Sao Paulo, Brazil

[5] Kings Coll London, Inst Psychiat, Ctr Neuroimaging Sci, Dept Neuroimaging, London WC2R 2LS, England

[6] Kings Coll London, Inst Psychiat, Social Genet & Dev Psychiat Ctr, London WC2R 2LS, England

来源：

MOLECULAR PSYCHIATRY | 2012年 / 17卷 / 12期

基金：

英国惠康基金; 美国国家卫生研究院; 英国医学研究理事会;

关键词：

VAL(158)MET MODERATION; GENETIC-VARIATION; DOPAMINE RELEASE; SCHIZOPHRENIA; HUMANS; RISK;

D O I：

10.1038/mp.2011.187

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

页码：1152 / 1155

页数：5

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