First report on cylindrospermopsin producing Aphanizomenon flos-aquae (Cyanobacteria) isolated from two German lakes

被引：180

作者：

Preussel, K

Stüken, A

Wiedner, C

Chorus, I

Fastner, J

机构：

[1] Fed Environm Agcy, D-14195 Berlin, Germany

[2] Inst Freshwater Ecol & Inland Fisheries, Dept Limnol Stratified Lakes, D-16775 Stechlin, Germany

来源：

TOXICON | 2006年 / 47卷 / 02期

关键词：

cylindrospermopsin; Aphanizomenon flos-aquae; Cyanobacteria; Germany;

D O I：

10.1016/j.toxicon.2005.10.013

中图分类号：

R9 [药学];

学科分类号：

1007 [药学];

摘要：

Three single-filament isolates of Aphanizomenon flos-aquae from two German lakes were found to produce remarkable amounts of the cyanobacterial hepatotoxin cylindrospermopsin (CYN). CYN-synthesis of the strains were evidenced both by LC-MS/MS analysis and detection of PCR products of gene fragments which are implicated in the biosynthesis of the toxin. The strains contain CYN in the range of 2.3-6.6 mg g(-1) of cellular dry weight. To our knowledge this is the first report of CYN in A. flos-aquae. (c) 2005 Elsevier Ltd. All rights reserved.

引用

收藏

页码：156 / 162

页数：7

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