Involvement of the chromosomal region 11q13 in renal oncocytoma: Case report and literature review

被引：39

作者：

Neuhaus, C

Dijkhuizen, T

vandenBerg, E

Storkel, S

Stockle, M

Mensch, B

Huber, C

Decker, HJ

机构：

[1] UNIV MAINZ,DEPT HEMATOL & ONCOL,D-55101 MAINZ,GERMANY

[2] UNIV MUNSTER,GERHARD DOMAGK INST PATHOL,D-4400 MUNSTER,GERMANY

[3] UNIV GRONINGEN,DEPT MED GENET,GRONINGEN,NETHERLANDS

来源：

CANCER GENETICS AND CYTOGENETICS | 1997年 / 94卷 / 02期

关键词：

D O I：

10.1016/S0165-4608(96)00205-1

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Renal oncocytomas comprise a cytogenetically heterogeneous group of tumors consisting potentially of cytogenetic distinguishable subgroups. Review of the literature revealed loss of chromosome 1 and Y as a possible anomaly for at least one subset of oncocytomas. The frequent finding of rearrangements involving chromosome 11 band q13 characterizes another subset of oncocytomas. We report the cytogenetic and pathological features of a renal oncocytoma diagnosed in a 72-year-old woman and found a t(9;11)(p23;q13) as a consistent abnormality. This supports the idea that translocations involving 11q13 define a further subset of oncocytoma. (C) Elsevier Science Inc., 1997.

引用

页码：95 / 98

页数：4

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