Oxidative synthesis of quinazolinones and benzothiadiazine 1,1-dioxides from 2-amino-benzamide and 2-aminobenzenesulfonamide with benzyl alcohols and aldehydes

被引：124

作者：

Sharif, Muhammad ^{[2
,4
]}

Opalach, Julita ^{[2
,3
]}

Langer, Peter ^{[2
,3
]}

Beller, Matthias ^{[2
]}

Wu, Xiao-Feng ^{[1
,2
]}

机构：

[1] Zhejiang Sci Tech Univ, Dept Chem, Hangzhou 310018, Zhejiang, Peoples R China

[2] Univ Rostock, Leibniz Inst Katalyse eV, D-18059 Rostock, Germany

[3] Univ Rostock, Inst Chem, D-18059 Rostock, Germany

[4] Comsats Inst Informat Technol, Dept Chem, Abbottabad 22060, Pakistan

来源：

RSC ADVANCES | 2014年 / 4卷 / 01期

关键词：

ONE-POT SYNTHESIS; ZINC-CATALYZED OXIDATION; IONIC LIQUID; HETEROCYCLES; ANTICANCER; EFFICIENT; QUINAZOLIN-4-(3H)-ONES; QUINAZOLIN-4(3H)-ONES; CYCLIZATION; INHIBITORS;

D O I：

10.1039/c3ra45765f

中图分类号：

O6 [化学];

学科分类号：

070301 [无机化学];

摘要：

An interesting procedure for the zinc-catalyzed oxidative transformation of ready available 2-aminobenzamide, 2-aminobenzenesulfonamide with benzyl alcohols has been developed. Various quinazolinones and benzothiadiazine 1,1-dioxides were prepared in moderate to good yields under identical conditions. The reactions of both aromatic aldehydes and aliphatic aldehydes with 2-aminobenzamide under catalyst free conditions were described as well. In water media, the products were formed in good yields.

引用

页码：8 / 17

页数：10

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