Syntheses of two cytotoxic polyunsaturated pyrrole metabolites of the marine sponge Mycale micracanthoxea

被引：20

作者：

Hansen, TV

Skattebol, L

机构：

[1] Univ Oslo, Sch Pharm, Dept Med Chem, N-0316 Oslo, Norway

[2] Univ Oslo, Dept Chem, N-0315 Oslo, Norway

来源：

TETRAHEDRON LETTERS | 2004年 / 45卷 / 13期

关键词：

pyrroles; synthesis; Stille coupling;

D O I：

10.1016/j.tetlet.2004.02.024

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Starting from eicosapentaenoic acid (EPA) the marine, naturally occurring, pyrrole derivatives, mycalazol 5 and mycalazal 2 have been synthesized. The Stille coupling reaction is a key step in the syntheses. (C) 2004 Elsevier Ltd. All rights reserved.

引用

收藏

页码：2809 / 2811

页数：3

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