Synthesis and biological activity of β-fluoroalkyl β-amino alcohols

被引：38

作者：

Bravo, P

Crucianelli, M

Ono, T

Zanda, M

机构：

[1] Politecn Milan, Dipartimento Chim, I-20131 Milan, Italy

[2] CNR, Ctr Studio Sostanze Organ Nat, I-20131 Milan, Italy

[3] Natl Ind Res Inst Nagoya, Kita Ku, Nagoya, Aichi 4628510, Japan

来源：

JOURNAL OF FLUORINE CHEMISTRY | 1999年 / 97卷 / 1-2期

基金：

日本科学技术振兴机构;

关键词：

fluoroalkyl; amino alcohols; florfenicol; synthesis; bioactivity; chiral;

D O I：

10.1016/S0022-1139(99)00024-X

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

This paper reviews the synthesis of unnatural chiral beta-fluoroalkyl beta-amino alcohols, with an emphasis on their biological activity and pharmaceutical applications. (C) 1999 Elsevier Science S.A, All rights reserved.

引用

页码：27 / 49

页数：23

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