Behavioral side effects of gabapentin in children

被引：106

作者：

Lee, DO

Steingard, RJ

Cesena, M

Helmers, SL

Riviello, JJ

Mikati, MA

机构：

[1] HARVARD UNIV,CHILDRENS HOSP,SCH MED,DEPT PSYCHIAT,BOSTON,MA 02115

[2] HARVARD UNIV,CHILDRENS HOSP,SCH MED,DEPT NEUROL,BOSTON,MA 02115

来源：

EPILEPSIA | 1996年 / 37卷 / 01期

关键词：

gabapentin; attention deficit with hyperactivity; adverse effects; child behavior;

D O I：

10.1111/j.1528-1157.1996.tb00517.x

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

We report 7 children who received gabapentin (GBP) as adjunctive medication and subsequently developed behavioral side effects. These behavioral changes consisted of intensification of baseline behaviors as well as new behavioral problems. Behaviors that parents considered most troublesome were tantrums, aggression directed toward others, hyperactivity, and defiance. All behavioral changes were reversible and were managed by dose reduction or discontinuation of GBP. All children had baseline attention deficit hyperactivity disorder and developmental delays.

引用

页码：87 / 90

页数：4

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