Evaluation of the TierPET system

被引：47

作者：

Weber, S

Herzog, H

Cremer, M

Engels, R

Hamacher, K

Kehren, F

Muehlensiepen, H

Ploux, L

Reinartz, R

Reinhart, P

Rongen, F

Sonnenberg, F

Coenen, HH

Halling, H

机构：

[1] Forschungszentrum Julich, Zent Lab Elektron, D-52425 Julich, Germany

[2] Forschungszentrum Julich, Inst Med, D-52425 Julich, Germany

[3] Forschungszentrum Julich, Inst Nukl Med, D-52425 Julich, Germany

来源：

IEEE TRANSACTIONS ON NUCLEAR SCIENCE | 1999年 / 46卷 / 04期

关键词：

D O I：

10.1109/23.790853

中图分类号：

TM [电工技术]; TN [电子技术、通信技术];

学科分类号：

0808 ; 0809 ;

摘要：

The TierPET system, a high resolution 3D positron emission tomograph, has been developed to perform small animal positron emission tomography (PET) studies. High resolution PET opens the possibility to perform animal trials without the need for vivisection. This reduces the number of animals and the costs for such experiments, for example concerning the development of new radiopharmaceuticals. The scanner uses two orthogonal pairs of detectors consisting of arrays of small individual YAP crystals coupled to position sensitive photomultipliers. The center-detector distance may be varied to improve either sensitivity or spatial resolution. The spatial resolution of the scanner is 2.1 mm.

引用

收藏

页码：1177 / 1183

页数：7

相关论文

共 23 条

[1]

[Anonymous], 1996, MATRIX COMPUTATIONS

[2] Three-dimensional performance of a small-diameter positron emission tomograph [J].

Bloomfield, PM ;

Myers, R ;

Hume, SP ;

Spinks, TJ ;

Lammertsma, AA ;

Jones, T .

PHYSICS IN MEDICINE AND BIOLOGY, 1997, 42 (02) :389-400

[3] Performance study of a 3D small animal PET scanner based on BaF2 crystals and a photo sensitive wire chamber [J].

Bruyndonckx, P ;

Liu, XA ;

Tavernier, S ;

Zhang, SP .

NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION A-ACCELERATORS SPECTROMETERS DETECTORS AND ASSOCIATED EQUIPMENT, 1997, 392 (1-3) :407-413

[4] MicroPET: A high resolution PET scanner for imaging small animals [J].

Cherry, SR ;

Shao, Y ;

Silverman, RW ;

Meadors, K ;

Siegel, S ;

Chatziioannou, A ;

Young, JW ;

Jones, WF ;

Moyers, JC ;

Newport, D ;

Boutefnouchet, A ;

Farquhar, TH ;

Andreaco, M ;

Paulus, MJ ;

Binkley, DM ;

Nutt, R ;

Phelps, ME .

IEEE TRANSACTIONS ON NUCLEAR SCIENCE, 1997, 44 (03) :1161-1166

[5] Use of a YRP:Ce matrix coupled to a position-sensitive photomultiplier for high resolution position emission tomography [J].

DelGuerra, A ;

deNotaristefani, F ;

DiDomenico, G ;

Giganti, M ;

Pani, R ;

Piffanelli, A ;

Zavattini, G .

IEEE TRANSACTIONS ON NUCLEAR SCIENCE, 1996, 43 (03) :1958-1962

[6] A small animal PET prototype based on LSO crystals read out by avalanche photodiodes [J].

Fries, O ;

Bradbury, SM ;

Gebauer, J ;

Holl, I ;

Lorenz, E ;

Renker, D ;

Ziegler, SI .

NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION A-ACCELERATORS SPECTROMETERS DETECTORS AND ASSOCIATED EQUIPMENT, 1997, 387 (1-2) :220-224

[7] ALGEBRAIC RECONSTRUCTION TECHNIQUES (ART) FOR 3-DIMENSIONAL ELECTRON MICROSCOPY AND X-RAY PHOTOGRAPHY [J].

GORDON, R ;

BENDER, R ;

HERMAN, GT .

JOURNAL OF THEORETICAL BIOLOGY, 1970, 29 (03) :471-&

[8] REMOTE-CONTROLLED ONE-STEP PRODUCTION OF F-18 LABELED BUTYROPHENONE NEUROLEPTICS EXEMPLIFIED BY THE SYNTHESIS OF NCA [F-18] N-METHYLSPIPERONE [J].

HAMACHER, K ;

HAMKENS, W .

APPLIED RADIATION AND ISOTOPES, 1995, 46 (09) :911-916

[9] Evaluation of 3D reconstruction algorithms for a small animal PET camera [J].

Johnson, CA ;

Seidel, J ;

Carson, RE ;

Gandler, WR ;

Sofer, A ;

Green, MV ;

DaubeWitherspoon, ME .

IEEE TRANSACTIONS ON NUCLEAR SCIENCE, 1997, 44 (03) :1303-1308

[10] 2-DIMENSIONAL NEUTRON SCINTILLATION DETECTOR WITH OPTIMAL GAMMA DISCRIMINATION [J].

KANYO, M ;

REINARTZ, R ;

SCHELTEN, J ;

MULLER, KD .

NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION A-ACCELERATORS SPECTROMETERS DETECTORS AND ASSOCIATED EQUIPMENT, 1992, 320 (03) :562-568