Relationship between biofilm formation, the enterococcal surface protein (Esp) and gelatinase in clinical isolates of Enterococcus faecalis and Enterococcus faecium

被引:122
作者
Di Rosa, R
Creti, R
Venditti, M
D'Amelio, R
Arciola, CR
Montanaro, L
Baldassarri, L
机构
[1] Ist Super Sanita, Dipartimento Malattie Infett Parassitarie & Immun, I-00161 Rome, Italy
[2] Fac Med 2, Cattedra Allergol & Immunol Clin, Rome, Italy
[3] Minist Difesa, Direz Gen Sanita Mil, Rome, Italy
[4] Univ Roma La Sapienza, Fac Med 1, Dipartimento Med Clin, Rome, Italy
[5] Ist Ortoped Rizzoli, Bologna, Italy
关键词
enterococci; biofilm; esp; gelatinase; virulence;
D O I
10.1111/j.1574-6968.2006.00112.x
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
One-hundred and twenty-eight enterococcal isolates were examined for their ability to form biofilm in relation to the presence of the gene encoding the enterococcal surface protein (esp), production of gelatinase and to the source of isolation. Neither esp nor gelatinase seemed to be required for biofilm formation: both Enterococcus faecalis and Enterococcus faecium did not show a correlation between the presence of either esp or the production of gelatinase and biofilm formation. However, in E. faecium while esp was found in isolates from either source, the presence of both esp and biofilm together was only found in strains from clinical settings, suggesting that there exists a synergy between these factors which serves as an advantage for the process of infection.
引用
收藏
页码:145 / 150
页数:6
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