Therapeutic perspectives on the combination of α-lipoic acid and vitamin E

被引：39

作者：

Gonzalez-Perez, O ^{[1
]}

Gonzalez-Castaneda, RE

机构：

[1] Univ Calif San Francisco, Neurosurg & Program Dev & Stem Cell Biol, San Francisco, CA 94143 USA

[2] Inst Mexicano Seguro Social, CIBO, Guadalajara 44340, Jalisco, Mexico

来源：

NUTRITION RESEARCH | 2006年 / 26卷 / 01期

关键词：

thioctic acid; alpha-tocopherol; antioxidants; vitamins; reactive oxygen species; lipid peroxidation;

D O I：

10.1016/j.nutres.2005.11.011

中图分类号：

R15 [营养卫生、食品卫生]; TS201 [基础科学];

学科分类号：

100403 ;

摘要：

alpha-Lipoic acid (ALA) and vitamin E (VE) have synergistic effects, as determined in models of oxidant radical lesions. This review summarizes recent findings showing that the combination of ALA plus VE has beneficial effects in reducing oxidative damage in ischemic or other oxidation-related pathologic events. Both antioxidants are common in the normal human diet, and side effects are very rare. Therefore, ALA and VE can counteract oxidative processes and could have an important role in clinical medicine. (C) 2006 Elsevier Inc. All rights reserved.

引用

页码：1 / 5

页数：5

共 57 条

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