Double emulsion templated monodisperse phospholipid vesicles

被引：301

作者：

Shum, Ho Cheung ^{[1
]}

Lee, Daeyeon ^{[1
]}

Yoon, Insun

Kodger, Tom ^{[1
]}

Weitz, David A. ^{[1
]}

机构：

[1] Harvard Univ, Sch Engn & Appl Sci, Cambridge, MA 02138 USA

来源：

LANGMUIR | 2008年 / 24卷 / 15期

关键词：

D O I：

10.1021/la801833a

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

We present a novel approach for fabricating monodisperse phospholipid vesicles with high encapsulation efficiency using controlled double emulsions as templates. Glass-capillary microfluidics is used to generate monodisperse double emulsion templates. We show that the high uniformity in size and shape of the templates are maintained in the final phospholipid vesicles after a solvent removal step. Our simple and versatile technique is applicable to a wide range of phospholipids.

引用

页码：7651 / 7653

页数：3

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