Microfluidics: Applications for analytical purposes in chemistry and biochemistry

被引:323
作者
Ohno, Ken-ichi [1 ]
Tachikawa, Kaoru [1 ]
Manz, Andreas [1 ]
机构
[1] Inst Analyt Sci, D-44139 Dortmund, Germany
关键词
Integrated systems; Multi-functionalisation; Point-of-care; Reaction; Separation;
D O I
10.1002/elps.200800121
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
In this review, we present recent advancements and novel developments in fluidic systems for applied analytical purposes in chemistry, biochemistry, and life science in general that employ and reflect the full benefits of microfluidics. A staggering rise in publications related to integrated, all-in-one microfluidic chips capable of separation, reaction, and detection have been observed, all of which realise the principal of micro total analysis systems or lab-on-a-chip. These integrated chips actively adopt the scaling law concepts, utilising the highly developed fabrication techniques. Their aim is to multi-functionalise and fully automate devices believed to assist the future advancements of point-of-care, clinical, and medical diagnostics.
引用
收藏
页码:4443 / 4453
页数:11
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