The growing family of mitochondrial carriers in Arabidopsis

被引:148
作者
Picault, N
Hodges, M
Paimieri, L
Palmieri, F
机构
[1] Univ Paris 11, CNRS, UMR 8618, Inst Biotechnol Plantes, F-91405 Orsay, France
[2] Univ Bari, Biochem & Mol Biol Lab, Dept Pharmaco Biol, I-70125 Bari, Italy
[3] CNR Inst Biomembranes & Bioenerget, I-70125 Bari, Italy
关键词
D O I
10.1016/j.tplants.2004.01.007
中图分类号
Q94 [植物学];
学科分类号
071001 ;
摘要
Plant mitochondria maintain metabolic communication with the cytosol through a family of carrier proteins that share several structural features. Early studies led to the recognition of several mitochondrial transport activities but the proteins responsible for these activities had not been identified. The in silico analysis of the complete Arabidopsis genome has revealed almost 60 genes encoding putative members of the mitochondrial carrier family. Recombinant protein technology and functional reconstitution techniques developed for animal and yeast carrier proteins are currently being combined with a wide range of functional-genomics tools to identify and characterize mitochondrial carriers in plants. This information is crucial for obtaining an integrated view of mitochondrial function in plant cell metabolism.
引用
收藏
页码:138 / 146
页数:9
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