Transcriptional profiling of Pseudomonas aeruginosa grown under steady-state hyperosmotic stress conditions showed an up-regulation of genes associated with osmoprotectant synthesis, putative hydrophilins, and the type III secretion system with associated cytotoxins. A large number of regulatory genes, including several two-component systems not previously known to be influenced by osmolarity, were differentially expressed by P. aeruginosa in immediate response to hyperosmotic shock.
机构:
Univ N Carolina, Cyst Fibrosis Pulm Res & Treatment Ctr, Dept Med, Chapel Hill, NC 27599 USAUniv N Carolina, Cyst Fibrosis Pulm Res & Treatment Ctr, Dept Med, Chapel Hill, NC 27599 USA
Donaldson, SH
;
Boucher, RC
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机构:
Univ N Carolina, Cyst Fibrosis Pulm Res & Treatment Ctr, Dept Med, Chapel Hill, NC 27599 USAUniv N Carolina, Cyst Fibrosis Pulm Res & Treatment Ctr, Dept Med, Chapel Hill, NC 27599 USA
机构:
Univ N Carolina, Cyst Fibrosis Pulm Res & Treatment Ctr, Dept Med, Chapel Hill, NC 27599 USAUniv N Carolina, Cyst Fibrosis Pulm Res & Treatment Ctr, Dept Med, Chapel Hill, NC 27599 USA
Donaldson, SH
;
Boucher, RC
论文数: 0引用数: 0
h-index: 0
机构:
Univ N Carolina, Cyst Fibrosis Pulm Res & Treatment Ctr, Dept Med, Chapel Hill, NC 27599 USAUniv N Carolina, Cyst Fibrosis Pulm Res & Treatment Ctr, Dept Med, Chapel Hill, NC 27599 USA