Acylation of anisole with methylsuccinic anhydride catalysed by zeolites

被引：2

作者：

Gaare, K ^{[1
]}

Akporiaye, D ^{[1
]}

Holm, K ^{[1
]}

Skattebol, L ^{[1
]}

机构：

[1] UNIV OSLO,DEPT CHEM,N-0315 OSLO,NORWAY

来源：

ACTA CHEMICA SCANDINAVICA | 1997年 / 51卷 / 12期

关键词：

D O I：

10.3891/acta.chem.scand.51-1229

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The zeolite-catalysed acylation of anisole with methylsuccinic anhydride gave mixture of products. The main component was 4-hydroxy-4,4-bis-(4-methoxyphenyl)-2-methyl-gamma-butyrolactone, which was isolated in 25% yield; the expected keto acids were not formed. In the zeolite-catalysed reaction between 3-(4-methoxybenzoyl)-2-methylpropionic acid and anisole, the gamma-butyrolactone was isolated in 82% yield, indicating that the initially formed keto acid undergoes cyclisation to the lactone. When these reactions were performed with a zeolite deactivated with triphenylphosphine, the lactone was not formed, suggesting that acid sites on the external surface of the zeolite catalyse these reactions.

引用

页码：1229 / 1233

页数：5