Salt-free synthesis of tertiary amines by ruthenium-catalyzed amination of alcohols

被引：106

作者：

Tillack, Annegret ^{[1
]}

Hollmann, Dirk ^{[1
]}

Mevius, Kathleen ^{[1
]}

Michalik, Dirk ^{[1
]}

Baehn, Sebastian ^{[1
]}

Beller, Matthias ^{[1
]}

机构：

[1] Univ Rostock, Leibniz Inst Katalyse eV, D-18059 Rostock, Germany

来源：

EUROPEAN JOURNAL OF ORGANIC CHEMISTRY | 2008年 / 2008卷 / 28期

关键词：

ruthenium; amination; alcohols;

D O I：

10.1002/ejoc.200800671

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The amination of secondary alcohols to give tertiary amines in the presence of different in situ generated ruthenium catalysts has been investigated in detail. By applying a combination of [Ru-3(CO)(12)] and N-phenyl-2-(dicyclohexylphosphanyl)pyrrole as the catalyst, cyclic amines can be alkylated with different alcohols in high yield, whereas aliphatic amines gave transalkylation side products. ((C) Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2008).

引用

页码：4745 / 4750

页数：6

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