NDR kinases regulate essential cell processes from yeast to humans

被引：264

作者：

Hergovich, A ^{[1
]}

Stegert, MR ^{[1
]}

Schmitz, D ^{[1
]}

Hemmings, BA ^{[1
]}

机构：

[1] Friedrich Miescher Inst Biomed Res, CH-4058 Basel, Switzerland

来源：

NATURE REVIEWS MOLECULAR CELL BIOLOGY | 2006年 / 7卷 / 04期

关键词：

D O I：

10.1038/nrm1891

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Members of the NDR ( nuclear Dbf2-related) protein-kinase family are essential components of pathways that control important cellular processes, such as morphological changes, mitotic exit, cytokinesis, cell proliferation and apoptosis. Recent progress has shed light on the mechanisms that underlie the regulation and function of the NDR family members. Combined data from yeast, worms, flies, mice and human cells now highlight the conserved and important roles of the different NDR kinases in distinct cellular processes.

引用

页码：253 / 264

页数：12

共 133 条

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