Functionalized mesoporous silicates for the removal of ruthenium from reaction mixtures

被引：62

作者：

McEleney, Kevin ^{[1
]}

Allen, Daryl P. ^{[1
]}

Holliday, Alison E. ^{[1
]}

Crudden, Cathleen M. ^{[1
]}

机构：

[1] Queens Univ, Dept Chem, Kingston, ON K7L 3N6, Canada

来源：

ORGANIC LETTERS | 2006年 / 8卷 / 13期

关键词：

D O I：

10.1021/ol060389g

中图分类号：

O62 [有机化学];

学科分类号：

070303 [有机化学]; 081704 [应用化学];

摘要：

The removal of residual ruthenium after olefin metathesis reactions and asymmetric hydrogenations has been described using amine-functionalized mesoporous silicates. Aminopropyltriethoxy silane-derivatized silicates were found to be the most effective. More than 99.99% of RuCl3 could be removed in a single treatment. Scavenging of Ru after metathesis reactions using a Grubbs generation 1 catalyst gave a product with concentrations of less than 10 mu g/5 mg after two treatments with amine-modified silica. Most importantly, no chromatography was required.

引用

页码：2663 / 2666

页数：4

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