Applications of nanomaterials in enantioseparation and related techniques

被引：79

作者：

Chang, Cuilan ^{[1
]}

Wang, Xin ^{[1
]}

Bai, Yu ^{[1
]}

Liu, Huwei ^{[1
]}

机构：

[1] Peking Univ, Key Lab Bioorgan Chem & Mol Engn, Beijing Natl Lab Mol Sci, Minist Educ,Inst Analyt Chem,Coll Chem & Mol Engn, Beijing 100871, Peoples R China

来源：

TRAC-TRENDS IN ANALYTICAL CHEMISTRY | 2012年 / 39卷

基金：

中国国家自然科学基金;

关键词：

Carbon nanotube; Enantioseparation; Magnetic nanomaterial; Mesoporous silica; Metal nanomaterial; Metal-organic framework; Nanomaterial; Organic polymer; Stationary phase; WALLED CARBON NANOTUBES; MOLECULARLY IMPRINTED POLYMERS; MODIFIED GOLD NANOPARTICLES; METAL-ORGANIC FRAMEWORKS; AMINO-ACIDS; ENANTIOMERIC SEPARATION; PSEUDOSTATIONARY PHASE; ASYMMETRIC CATALYSIS; CHIRAL RECOGNITION; BETA-CYCLODEXTRIN;

D O I：

10.1016/j.trac.2012.07.002

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

Chirality is an important, universal phenomenon in nature. For the in-depth study of pharmacology and biology, efficient enantioselective technologies are indispensable. Nanomaterials with large surface-to-volume ratio and specific physical and chemical properties have demonstrated great potential in chiral discrimination. Many publications show that utilization of nanomaterials could improve the selectivity, the stability and the efficiency of enantioseparation. This review summarizes the applications of various enantioselective nanomaterials, including mesoporous silica, organic polymers, metal-organic frameworks, metal nanomaterials, magnetic nanomaterials, carbon nanotubes and well-oriented chiral nanolayers. After proper preparation and modification, these functionalized nanomaterials are effective for chiral separation through their specific enantioselective adsorption, especially when they are used as stationary or pseudo-stationary phases in chiral chromatographic separation, such as thin-layer chromatography, high-performance liquid chromatography, gas chromatography and capillary electrophoresis. (c) 2012 Elsevier Ltd. All rights reserved.

引用

页码：195 / 206

页数：12

共 88 条

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