The role of the PI3K-PKB signaling module in regulation of hematopoiesis

被引:63
作者
Buitenhuis, Miranda [1 ]
Coffer, Paul J. [1 ,2 ]
机构
[1] Univ Med Ctr, Dept Immunol, Mol Immunol Lab, NL-3584 CX Utrecht, Netherlands
[2] Univ Med Ctr, Dept Pediat Immunol, NL-3584 CX Utrecht, Netherlands
关键词
hematopoiesis; PI3K; PKB; signal transduction; lineage development; self-renewal; hematopoietic stem cells; ACUTE MYELOID-LEUKEMIA; FORKHEAD TRANSCRIPTION FACTOR; PROTEIN-KINASE-B; GLYCOGEN-SYNTHASE KINASE-3; MICE LACKING; PHOSPHOINOSITIDE; 3-KINASE; STEM-CELLS; DEFICIENT MICE; PHOSPHATIDYLINOSITOL 3,4,5-TRISPHOSPHATE; SUBSTRATE-SPECIFICITY;
D O I
10.4161/cc.8.4.7654
中图分类号
Q2 [细胞生物学];
学科分类号
071013 [干细胞生物学];
摘要
[No abstract available]
引用
收藏
页码:560 / 566
页数:7
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