Asymmetric dihydroxylation and regioselective C-3 indole coupling routes to the anticoccidial antibiotic (+)-diolmycin A2

被引：14

作者：

Fernandes, RA ^{[1
]}

Bodas, MS ^{[1
]}

Kumar, P ^{[1
]}

机构：

[1] Natl Chem Lab, Div Organ Chem Technol, Pune 411008, Maharashtra, India

来源：

TETRAHEDRON | 2002年 / 58卷 / 06期

关键词：

asymmetric synthesis; dihydroxylation; epoxide; regioselective alkylation; indole; anticoccidial antibiotic;

D O I：

10.1016/S0040-4020(01)01219-4

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A highly enantioselective synthesis of (+)-diolmycin A2 starting from 4-hydroxybenzaldehyde and employing the Sharpless asymmetric dihydroxylation and CH3NO2 solvent assisted regioselective C-3 coupling of indole as the key steps is described. (C) 2002 Elsevier Science Ltd. All rights reserved.

引用

页码：1223 / 1227

页数：5

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